Cloning and Characterization of Oxidosqualene Cyclases from Kalanchoe daigremontiana: ENZYMES CATALYZING UP TO 10 REARRANGEMENT STEPS YIELDING FRIEDELIN AND OTHER TRITERPENOIDS

The first committed step in triterpenoid biosynthesis is the cyclization of oxidosqualene to polycyclic alcohols or ketones C(30)H(50)O. It is catalyzed by single oxidosqualene cyclase (OSC) enzymes that can carry out varying numbers of carbocation rearrangements and, thus, generate triterpenoids wi...

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Autores principales: Wang, Zhonghua, Yeats, Trevor, Han, Hong, Jetter, Reinhard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Plant Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943309/
https://ncbi.nlm.nih.gov/pubmed/20610397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098871
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