Phosphorylation of Lysophosphatidylcholine Acyltransferase 2 at Ser(34) Enhances Platelet-activating Factor Production in Endotoxin-stimulated Macrophages

Platelet-activating factor (PAF) is a potent proinflammatory phospholipid mediator that elicits various cellular functions under physiological and pathological conditions. We have recently identified two enzymes involved in PAF production: lysophosphatidylcholine acyltransferase-1 (LPCAT1) and LPCAT...

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Autores principales: Morimoto, Ryo, Shindou, Hideo, Oda, Yoshiya, Shimizu, Takao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Lipids
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943291/
https://ncbi.nlm.nih.gov/pubmed/20663880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147025
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