Heparin inhibits the induction of three matrix metalloproteinases (stromelysin, 92-kD gelatinase, and collagenase) in primate arterial smooth muscle cells.

Heparin inhibits the migration and proliferation of arterial smooth muscle cells and modifies the extracellular matrix. These effects may be the result of heparin's effects on proteinases that degrade the matrix. We have previously reported that heparin inhibits the induction of tissue-type plasmino...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Kenagy, R D, Nikkari, S T, Welgus, H G, Clowes, A W
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294307/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8182130/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117191
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