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Cytokines suppress human islet function irrespective of their effects on nitric oxide generation.

Cytokines have been proposed as inducers of beta-cell damage in human insulin-dependent diabetes mellitus via the generation of nitric oxide (NO). This concept is mostly based on data obtained in rodent pancreatic islets using heterologous cytokine preparations. The present study examined whether ex...

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Autors principals: Eizirik, D L, Sandler, S, Welsh, N, Cetkovic-Cvrlje, M, Nieman, A, Geller, D A, Pipeleers, D G, Bendtzen, K, Hellerström, C
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC294304/
https://ncbi.nlm.nih.gov/pubmed/7514190
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