Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene.

Brain natriuretic peptide (BNP) is a cardiac hormone that occurs predominantly in the ventricle. To study the roles of BNP in chronic cardiovascular regulation, we isolated mouse BNP cDNA and genomic clones, and generated transgenic mice with elevated plasma BNP concentration. The mouse BNP gene was...

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Detalhes bibliográficos
Main Authors: Ogawa, Y, Itoh, H, Tamura, N, Suga, S, Yoshimasa, T, Uehira, M, Matsuda, S, Shiono, S, Nishimoto, H, Nakao, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC294298/
https://ncbi.nlm.nih.gov/pubmed/8182124
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