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Structure of the RNA binding domain of a DEAD-box helicase bound to its ribosomal RNA target reveals a novel mode of recognition by an RNA recognition motif

DEAD-box RNA helicases of the bacterial DbpA subfamily are localized to their biological substrate when a carboxy-terminal RNA recognition motif (RRM) domain binds tightly and specifically to a segment of 23S ribosomal RNA (rRNA) that includes hairpin 92 of the peptidyl transferase center. A complex...

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Detalhes bibliográficos
Main Authors: Hardin, John W., Hu, YaoXiong, McKay, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942969/
https://ncbi.nlm.nih.gov/pubmed/20673833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.07.040
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