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Dual regulation of mu opioid receptors in SK-N-SH neuroblastoma cells by morphine and interleukin-1β: evidence for opioid-immune crosstalk

Treatment of SK-N-SH cells with morphine and interleukin-1beta (IL-1β) produced dual regulation of the mRNA for the human mu opioid receptor (MOR) protein. Morphine produced a decrease in the MOR mRNA while IL-1β increased it, as assessed by real-time quantitative PCR. These data were consistent wit...

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Detalhes bibliográficos
Main Authors: Mohan, Shekher, Davis, Randall L., DeSilva, Udaya, Stevens, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942958/
https://ncbi.nlm.nih.gov/pubmed/20615556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.06.007
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