Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum

BACKGROUND: Cerebellar corticogenesis begins with the assembly of Purkinje cells into the Purkinje plate (PP) by embryonic day 14.5 (E14.5) in mice. Although the dependence of PP formation on the secreted protein Reelin is well known and a prevailing model suggests that Purkinje cells migrate along...

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Bibliographic Details
Main Authors: Miyata, Takaki, Ono, Yuichi, Okamoto, Mayumi, Masaoka, Makoto, Sakakibara, Akira, Kawaguchi, Ayano, Hashimoto, Mitsuhiro, Ogawa, Masaharu
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942860/
https://ncbi.nlm.nih.gov/pubmed/20809939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-5-23
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