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Positive autoregulation shapes response timing and intensity in two-component signal transduction systems

Positive feedback loops are regulatory elements that can modulate expression output, kinetics and noise in genetic circuits. Transcriptional regulators participating in such loops are often expressed from two promoters – one constitutive and one autoregulated. Here we investigate the interplay of pr...

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Bibliografiska uppgifter
Huvudupphovsmän: Mitrophanov, Alexander Y., Hadley, Tricia J., Groisman, Eduardo A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942797/
https://ncbi.nlm.nih.gov/pubmed/20600106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.051
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