Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease.

Hydrolysis of glucosylceramide by beta-glucocerebrosidase results in ceramide, a critical component of the intercellular lamellae that mediate the epidermal permeability barrier. A subset of type 2 Gaucher patients displays ichthyosiform skin abnormalities, as do transgenic Gaucher mice homozygous f...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Holleran, W M, Ginns, E I, Menon, G K, Grundmann, J U, Fartasch, M, McKinney, C E, Elias, P M, Sidransky, E
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC294236/
https://ncbi.nlm.nih.gov/pubmed/8163674
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items