Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice.

Increased production of EGF or TGF-alpha by the respiratory epithelial cells has been associated with the pathogenesis of various forms of lung injury. Growth factors and cytokines are thought to act locally, via paracrine and autocrine mechanisms, to stimulate cell proliferation and matrix depositi...

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Autori principali: Korfhagen, T R, Swantz, R J, Wert, S E, McCarty, J M, Kerlakian, C B, Glasser, S W, Whitsett, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC294218/
https://ncbi.nlm.nih.gov/pubmed/8163670
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