Anthrax Toxin Receptor 1 / Tumor Endothelial Marker 8: Mutation of Conserved Inserted Domain Residues Overrides Cytosolic Control of Protective Antigen Binding

Anthrax toxin receptor 1 (ANTXR1) / tumor endothelial marker 8 (TEM8) is one of two known proteinaceous cell surface anthrax toxin receptors. A metal ion dependent adhesion site (MIDAS) present in the integrin-like inserted (I) domain of ANTXR1 mediates the binding of the anthrax toxin subunit, prot...

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Main Authors: Ramey, Jordan D., Villareal, Valerie A., Ng, Charles, Ward, Sabrina, Xiong, Jian-Ping, Clubb, Robert T., Bradley, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942075/
https://ncbi.nlm.nih.gov/pubmed/20690680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100887w
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