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Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes
Myosin VIIa functions in the outer retina, and loss of this function causes human blindness in Usher syndrome type 1B (USH1B). In mice with mutant Myo7a, melanosomes in the retinal pigmented epithelium (RPE) are distributed abnormally. In this investigation we detected many proteins in RPE cells tha...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2942070/ https://ncbi.nlm.nih.gov/pubmed/15572405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.01580 |
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