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Phosphorylation of GIT1 tyrosine-392 is required for PLCγ activation and podosome formation in vascular smooth muscle cells
OBJECTIVE: Podosomes, actin-rich structures, contribute to cell motility, matrix remodeling and tissue remodeling. We have shown that G-protein coupled receptor kinase 2-interacting protein 1 (GIT1) co-localizes with podosomes, and is important in podosome formation in endothelial cells. Src stimula...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941990/ https://ncbi.nlm.nih.gov/pubmed/20689073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.212415 |
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