Safety, Pharmacokinetics, and Pharmacodynamics of the Insulin-Like Growth Factor Type 1 Receptor Inhibitor Figitumumab (CP-751,871) in Combination with Paclitaxel and Carboplatin

Eitemau Tebyg

• Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing’s sarcoma: a phase 1 expansion cohort study
  gan: Olmos, David, et al.
  Cyhoeddwyd: (2009)
• The insulin-like growth factor-I receptor inhibitor figitumumab (CP-751,871) in combination with docetaxel in patients with advanced solid tumours: results of a phase Ib dose-escalation, open-label study
  gan: Molife, L R, et al.
  Cyhoeddwyd: (2010)
• The IGF-1 Receptor Targeting Antibody, CP-751,871, Suppresses Tumor-Derived VEGF and Synergizes with Rapamycin in Models of Childhood Sarcoma
  gan: Kurmasheva, Raushan T., et al.
  Cyhoeddwyd: (2009)
• Pre-treatment levels of circulating free IGF-1 identify NSCLC patients who derive clinical benefit from figitumumab
  gan: Gualberto, A, et al.
  Cyhoeddwyd: (2011)
• Pre-treatment levels of circulating free IGF-1 identify NSCLC patients who derive clinical benefit from figitumumab
  gan: Gualberto, A, et al.
  Cyhoeddwyd: (2012)