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Urotensin II-induced signaling involved in proliferation of vascular smooth muscle cells

The urotensin II receptor, bound by the ligand urotensin II, generates second messengers, ie, inositol triphosphate and diacylglycerol, which stimulate the subsequent release of calcium (Ca(2+)) in vascular smooth muscle cells. Ca(2+) influx leads to the activation of Ca(2+)-dependent kinases (CaMK)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Iglewski, Myriam, Grant, Stephen R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941785/
https://ncbi.nlm.nih.gov/pubmed/20859543
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