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Down-regulation of porin M35 in Moraxella catarrhalis by aminopenicillins and environmental factors and its potential contribution to the mechanism of resistance to aminopenicillins

OBJECTIVES: The outer membrane protein M35 of Moraxella catarrhalis is an antigenically conserved porin. Knocking out M35 significantly increases the MICs of aminopenicillins. The aim of this study was to determine the biological mechanism of this potentially new antimicrobial resistance mechanism o...

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Библиографические подробности
Главные авторы: Jetter, Marion, Spaniol, Violeta, Troller, Rolf, Aebi, Christoph
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941675/
https://ncbi.nlm.nih.gov/pubmed/20801781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq312
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