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Neuregulin/ErbB Signaling Regulates Cardiac Subtype Specification in Differentiating Human Embryonic Stem Cells

RATIONALE: Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) exhibit either a “working” chamber or a nodal-like phenotype. To generate optimal hESC-CM preparations for eventual clinical application in cell-based therapies, we will need to control their differentiation into these specialize...

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Detalhes bibliográficos
Main Authors: Zhu, Wei-Zhong, Xie, Yiheng, Moyes, Kara White, Gold, Joseph D., Askari, Bardia, Laflamme, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941561/
https://ncbi.nlm.nih.gov/pubmed/20671236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.223917
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