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Physico-mechanical aspects of extracellular matrix influences on tumorigenic behaviors

Tumor progression in vitro has traditionally been studied in the context of two-dimensional (2D) environments. However, it is now well accepted that 2D substrates are unnaturally rigid compared to the physiological substrate known as extracellular matrix (ECM) that is in direct contact with both nor...

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Detalhes bibliográficos
Main Authors: Cukierman, Edna, Bassi, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941524/
https://ncbi.nlm.nih.gov/pubmed/20452434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2010.04.004
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