The urokinase receptor is required for human monocyte chemotaxis in vitro.

Mononuclear phagocytes (Mphi) produce urokinase-type plasminogen activator (uPA) and also express a specific cell-surface receptor for urokinase, uPAR. The concomitant expression of these proteins provides a mechanism by which Mphi can degrade extracellular matrix proteins during directed cell migra...

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Bibliographic Details

Published in:	J Clin Invest
Main Authors:	Gyetko, M R, Todd, R F, Wilkinson, C C, Sitrin, R G
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 1994
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294150/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8163642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117114
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