Impaired Metabolic Effects of a Thyroid Hormone Receptor Beta-Selective Agonist in a Mouse Model of Diet-Induced Obesity

BACKGROUND: The use of selective agonists of the thyroid hormone receptor isoform β (TRβ) has been linked to metabolic improvement in animal models of diet-induced obesity, nonalcoholic liver disease, and genetic hypercholesterolemia. METHODS: To identify potential target tissues of such compounds,...

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Autors principals: Castillo, Melany, Freitas, Beatriz C.G., Rosene, Matthew L., Drigo, Rafael A., Grozovsky, Renata, Maciel, Rui M.B., Patti, Mary Elizabeth, Ribeiro, Miriam O., Bianco, Antonio C.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
Matèries:
Original Studies, Reviews, and Scholarly Dialog
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941403/
https://ncbi.nlm.nih.gov/pubmed/20406106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2009.0318
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