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Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

Intracellular detection of virus infections is a critical component of innate immunity carried out by molecules known as pathogen recognition receptors (PRRs). Activation of PRRs by their respective pathogen-associated molecular patterns (PAMPs) leads to production of proinflamatory cytokines, inclu...

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Detalhes bibliográficos
Main Authors: Baum, Alina, Sachidanandam, Ravi, García-Sastre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941304/
https://ncbi.nlm.nih.gov/pubmed/20805493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005077107
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