5-HT(1A) autoreceptor levels determine vulnerability to stress and response to antidepressants

Most depressed patients don't respond to their first drug treatment, and the reasons for this treatment resistance remain enigmatic. Human studies implicate a polymorphism in the promoter of the serotonin-1A (5-HT(1A)) receptor gene in increased susceptibility to depression and decreased treatm...

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Bibliographic Details
Main Authors: Richardson-Jones, Jesse W, Craige, Caryne P, Guiard, Bruno P, Stephen, Alisson, Metzger, Kayla L, Kung, Hank F, Gardier, Alain M, Dranovsky, Alex, David, Denis J, Beck, Sheryl G, Hen, René, Leonardo, E David
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941196/
https://ncbi.nlm.nih.gov/pubmed/20152112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.12.003
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