Genome-based Characterization of Two Prenylation Steps in the Assembly of the Stephacidin and Notoamide Anticancer Agents in a Marine-derived Aspergillus sp

Stephacidin and notoamide natural products belong to a group of prenylated indole alkaloids containing a core bicyclo[2.2.2]diazaoctane ring system. These bioactive fungal secondary metabolites have a range of unusual structural and stereochemical features but their biosynthesis has remained unchara...

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Hlavní autoři: Ding, Yousong, de Wet, Jeffrey R., Cavalcoli, James, Li, Shengying, Greshock, Thomas J., Miller, Kenneth A., Finefield, Jennifer M., Sunderhaus, James D., McAfoos, Timothy, Tsukamoto, Sachiko, Williams, Robert M., Sherman, David H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941195/
https://ncbi.nlm.nih.gov/pubmed/20722388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1049302
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