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Effect of High versus Low Oral Doses of Valacyclovir on Herpes Simplex Virus-1 DNA Shedding into Tears of Latently Infected Rabbits

PURPOSE. To assess the effect of high doses of valacyclovir (VCV) on HSV-1 DNA shedding into tears of latently infected rabbits. METHODS. Three oral doses of VCV were tested. Corneas were inoculated with HSV-1, and latent infection was allowed to establish. Starting on postinoculation (PI) day 28, t...

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Detalhes bibliográficos
Main Authors: Kumar, Manish, Kaufman, Herbert E., Clement, Christian, Bhattacharjee, Partha S., Huq, Tashfin S., Varnell, Emily D., Thompson, Hilary W., Hill, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941183/
https://ncbi.nlm.nih.gov/pubmed/20393107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4884
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