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Monoallelic Expression of Krt12 Gene during Corneal-type Epithelium Differentiation of Limbal Stem Cells

PURPOSE. The purpose of this study was to characterize a Krt12-Cre knock-in mouse line for corneal epithelium-specific gene ablation and to analyze the allelic selection of the keratin 12 (Krt12) gene during corneal type-epithelium differentiation. METHODS. Knock-in mice were generated by gene targe...

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Détails bibliographiques
Auteurs principaux: Hayashi, Yasuhito, Call, Mindy K., Liu, Chia-Yang, Hayashi, Miyuki, Babcock, George, Ohashi, Yuichi, Kao, Winston W.-Y.
Format: Artigo
Langue:Inglês
Publié: Association for Research in Vision and Ophthalmology, Inc. 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941181/
https://ncbi.nlm.nih.gov/pubmed/20393120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5331
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