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Altered Ferritin Subunit Composition: Change in Iron Metabolism in Lens Epithelial Cells and Downstream Effects on Glutathione Levels and VEGF Secretion

PURPOSE. The iron storage protein ferritin is necessary for the safe storage of iron and for protection against the production of iron-catalyzed oxidative damage. Ferritin is composed of 24 subunits of two types: heavy (H) and light (L). The ratio of these subunits is tissue specific, and alteration...

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Autors principals: Harned, Jill, Ferrell, Jenny, Lall, Marilyn M., Fleisher, Lloyd N., Nagar, Steven, Goralska, Małgorzata, McGahan, M. Christine
Format: Artigo
Idioma:Inglês
Publicat: Association for Research in Vision and Ophthalmology, Inc. 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941172/
https://ncbi.nlm.nih.gov/pubmed/20805568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3861
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