Biodegradable Poly(Ethylene Glycol) Hydrogels Based on a Self-Elimination Degradation Mechanism

Two vinyl sulfone functionalized crosslinkers were developed for the purpose of preparing degradable poly(ethylene glycol) (PEG) hydrogels (EMXL and GABA-EMXL hydrogels). A self-elimination degradation mechanism in which an N-terminal residue of a glutamine is converted to pyroglutamic acid with sub...

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Bibliographic Details
Main Authors: Deshmukh, Manjeet, Singh, Yashveer, Gunaseelan, Simi, Gao, Dayuan, Stein, Stanley, Sinko, Patrick J.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941153/
https://ncbi.nlm.nih.gov/pubmed/20561680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.05.021
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