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Kinetic basis for global loss of fidelity arising from mismatches in the P-site codon:anticodon helix
Faithful decoding of the genetic information by the ribosome relies on kinetically driven mechanisms that promote selection of cognate substrates during elongation. Recently, we have shown that in addition to these kinetically driven mechanisms, the ribosome possesses a post peptidyl transfer qualit...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941106/ https://ncbi.nlm.nih.gov/pubmed/20724456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2241810 |
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