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Kinetic basis for global loss of fidelity arising from mismatches in the P-site codon:anticodon helix

Faithful decoding of the genetic information by the ribosome relies on kinetically driven mechanisms that promote selection of cognate substrates during elongation. Recently, we have shown that in addition to these kinetically driven mechanisms, the ribosome possesses a post peptidyl transfer qualit...

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Detalhes bibliográficos
Main Authors: Zaher, Hani S., Green, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941106/
https://ncbi.nlm.nih.gov/pubmed/20724456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2241810
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