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Induction of immune unresponsiveness to concordant islet xenografts by intrahepatic preimmunization and transient immunosuppression.

Streptozotocin-induced, diabetic mice (C57BL/6) were preimmunized by injecting 25 low temperature, cultured Wistar-Furth (WF) rat islets into the portal vein, and the recipients received one injection of mouse and rat antilymphocyte sera. 3 wk later, fresh WF islets were transplanted under the kidne...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Goss, J A, Finke, E H, Flye, M W, Lacy, P E
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117088
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