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Timing of Immune Escape Linked to Success or Failure of Vaccination

Successful vaccination against HIV should limit viral replication sufficiently to prevent the emergence of viral immune escape mutations. Broadly directed immunity is likely to be required to limit opportunities for immune escape variants to flourish. We studied the emergence of an SIV Gag cytotoxic...

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Détails bibliographiques
Auteurs principaux: Reece, Jeanette C., Loh, Liyen, Alcantara, Sheilajen, Fernandez, Caroline S., Stambas, John, Sexton, Amy, De Rose, Robert, Petravic, Janka, Davenport, Miles P., Kent, Stephen J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940906/
https://ncbi.nlm.nih.gov/pubmed/20862289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012774
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