Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study

BACKGROUND: Mitomycin C is a chemotherapeutic agent used in the treatment of peritoneal surface malignancies, administered as hyperthermic intraperitoneal chemotherapy after cytoreductive surgery. Pharmacokinetic studies have been based on analyses of blood, urine and abdominal perfusate, but actual...

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Bibliografiske detaljer
Main Authors: Sørensen, Olaf, Andersen, Anders, Olsen, Harald, Alexandr, Kristian, Ekstrøm, Per Olaf, Giercksky, Karl-Erik, Flatmark, Kjersti
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940807/
https://ncbi.nlm.nih.gov/pubmed/20809961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-469
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