Bisphosphonate treatment of aggressive primary, recurrent and metastatic Giant Cell Tumour of Bone

BACKGROUND: Giant cell tumour of bone (GCTB) is an expansile osteolytic tumour which contains numerous osteoclast-like giant cells. GCTB frequently recurs and can produce metastatic lesions in the lungs. Bisphosphonates are anti-resorptive drugs which act mainly on osteoclasts. METHOD: In this study...

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Main Authors: Balke, Maurice, Campanacci, Laura, Gebert, Carsten, Picci, Piero, Gibbons, Max, Taylor, Richard, Hogendoorn, Pancras, Kroep, Judith, Wass, John, Athanasou, Nicholas
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940802/
https://ncbi.nlm.nih.gov/pubmed/20799989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-462
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