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Cocaine differentially inhibits neuronal differentiation and proliferation in vitro.

The outcome of in utero cocaine exposure is unclear. To determine if cocaine affects neuronal growth and differentiation, we used PC-12 cells, which have a mitogenic response to IGF-I and differentiate into neurons on exposure to nerve growth factor. Differentiation was quantified as neurite extensi...

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Autors principals: Zachor, D, Cherkes, J K, Fay, C T, Ocrant, I
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC294069/
https://ncbi.nlm.nih.gov/pubmed/8132758
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