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IGF-I Activation of the AKT Pathway Is Impaired in Visceral But Not Subcutaneous Preadipocytes from Obese Subjects

Obesity morbidity is associated with excess visceral adiposity, whereas sc adipose tissue is much less metabolically hazardous. Human abdominal sc preadipocytes have greater capacity for proliferation, differentiation, and survival than omental preadipocytes. IGF-I is a critical mediator of preadipo...

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Sonraí Bibleagrafaíochta
Main Authors: Cleveland-Donovan, Kelly, Maile, Laura A., Tsiaras, William G., Tchkonia, Tamara, Kirkland, James L., Boney, Charlotte M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Endocrine Society 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940538/
https://ncbi.nlm.nih.gov/pubmed/20555032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0043
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