FoxM1 Is Up-Regulated by Obesity and Stimulates β-Cell Proliferation

β-Cell mass expansion is one mechanism by which obese animals compensate for insulin resistance and prevent diabetes. FoxM1 is a transcription factor that can regulate the expression of multiple cell cycle genes and is necessary for the maintenance of adult β-cell mass, β-cell proliferation, and glu...

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Main Authors: Davis, Dawn Belt, Lavine, Jeremy A., Suhonen, Joshua I., Krautkramer, Kimberly A., Rabaglia, Mary E., Sperger, Jamie M., Fernandez, Luis A., Yandell, Brian S., Keller, Mark P., Wang, I-Ming, Schadt, Eric E., Attie, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940473/
https://ncbi.nlm.nih.gov/pubmed/20660304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0082
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