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Signaling from the Secretory Granule to the Nucleus: Uhmk1 and PAM

Neurons and endocrine cells package peptides in secretory granules (large dense-core vesicles) for storage and stimulated release. Studies of peptidylglycine α-amidating monooxygenase (PAM), an essential secretory granule membrane enzyme, revealed a pathway that can relay information from secretory...

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Detalhes bibliográficos
Main Authors: Francone, Victor P., Ifrim, Marius F., Rajagopal, Chitra, Leddy, Christopher J., Wang, Yanping, Carson, John H., Mains, Richard E., Eipper, Betty A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940467/
https://ncbi.nlm.nih.gov/pubmed/20573687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0381
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