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Targeting the mammalian target of Rapamycin to inhibit VEGF and cytokines for the treatment of primary effusion lymphoma

Primary effusion lymphoma (PEL) is a fatal malignancy, which typically presents as a lymphomatous effusion that later disseminates. Rapamycin (Rapa), which targets mTOR (mammalian target of Rapa), is currently evaluated as a treatment for PEL, but the recent development of PEL in Rapa-treated post-t...

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Detalhes bibliográficos
Main Authors: Gasperini, Paola, Tosato, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940422/
https://ncbi.nlm.nih.gov/pubmed/19554030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.117
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