Fatty Acid Synthase Polymorphisms, Tumor Expression, Body Mass Index, Prostate Cancer Risk, and Survival

PURPOSE: Fatty acid synthase (FASN) regulates de novo lipogenesis, body weight, and tumor growth. We examined whether common germline single nucleotide polymorphisms (SNPs) in the FASN gene affect prostate cancer (PCa) risk or PCa-specific mortality and whether these effects vary by body mass index...

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Hlavní autoři: Nguyen, Paul L., Ma, Jing, Chavarro, Jorge E., Freedman, Matthew L., Lis, Rosina, Fedele, Giuseppe, Fiore, Christopher, Qiu, Weiliang, Fiorentino, Michelangelo, Finn, Stephen, Penney, Kathryn L., Eisenstein, Anna, Schumacher, Fredrick R., Mucci, Lorelei A., Stampfer, Meir J., Giovannucci, Edward, Loda, Massimo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2010
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940394/
https://ncbi.nlm.nih.gov/pubmed/20679621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.27.0793
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