Fatty Acid Synthase Polymorphisms, Tumor Expression, Body Mass Index, Prostate Cancer Risk, and Survival

PURPOSE: Fatty acid synthase (FASN) regulates de novo lipogenesis, body weight, and tumor growth. We examined whether common germline single nucleotide polymorphisms (SNPs) in the FASN gene affect prostate cancer (PCa) risk or PCa-specific mortality and whether these effects vary by body mass index...

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Main Authors: Nguyen, Paul L., Ma, Jing, Chavarro, Jorge E., Freedman, Matthew L., Lis, Rosina, Fedele, Giuseppe, Fiore, Christopher, Qiu, Weiliang, Fiorentino, Michelangelo, Finn, Stephen, Penney, Kathryn L., Eisenstein, Anna, Schumacher, Fredrick R., Mucci, Lorelei A., Stampfer, Meir J., Giovannucci, Edward, Loda, Massimo
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Clinical Oncology 2010
Assuntos:
Original Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940394/
https://ncbi.nlm.nih.gov/pubmed/20679621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.27.0793
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