The Aryl hydrocarbon Receptor (AhR) interacts with c-Maf to promote the differentiation of IL-27-induced regulatory type 1 (T(R)1) cells

IL-10 producing regulatory type 1 (T(R)1) T cells are instrumental in the prevention of tissue inflammation, autoimmunity and graft-versus-host disease. The transcription factor c-Maf is essential for T(R)1 induction of IL-10, but the molecular mechanisms leading to the development of these cells re...

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Bibliografiske detaljer
Main Authors: Apetoh, Lionel, Quintana, Francisco J., Pot, Caroline, Joller, Nicole, Xiao, Sheng, Kumar, Deepak, Burns, Evan J., Sherr, David H., Weiner, Howard L., Kuchroo, Vijay K.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940320/
https://ncbi.nlm.nih.gov/pubmed/20676095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1912
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