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HIV Fusion Peptide Penetrates, Disorders, and Softens T-Cell Membrane Mimics

This work investigates the interaction of N-terminal gp41 fusion peptide (FP) of human immunodeficiency virus type 1 (HIV-1) with model membranes in order to elucidate how FP leads to fusion of HIV and T-cell membranes. FP constructs were (i) wild-type FP23 (23 N-terminal amino acids of gp41), (ii)...

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Detalhes bibliográficos
Main Authors: Tristram-Nagle, Stephanie, Chan, Rob, Kooijman, Edgar, Uppamoochikkal, Pradeep, Qiang, Wei, Weliky, David P., Nagle, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940274/
https://ncbi.nlm.nih.gov/pubmed/20655315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.07.026
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