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Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: Implications for early intervention on disease progression

We previously demonstrated that elevation of astrocytic monoamine oxidase B (MAO-B) levels in a doxycycline (dox)-inducible transgenic mouse model following 14 days of dox induction results in several neuropathologic features similar to those observed in the Parkinsonian midbrain (Mallajosyula et al...

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Bibliographische Detailangaben
Hauptverfasser: Siddiqui, Almas, Mallajosyula, Jyothi K., Rane, Anand, Andersen, Julie K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940273/
https://ncbi.nlm.nih.gov/pubmed/20655384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.07.004
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