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Role of the complement components C5 and C3a in a mouse model of myocardial ischemia and reperfusion injury

Objective: Ischemic heart disease is the leading cause of death worldwide. The complement system plays a major role in inflammation and tissue injury following myocardial ischemia and reperfusion (MI/R) injury. Systemic C5 inhibition in clinical studies has resulted in mixed results and the role of...

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Detalhes bibliográficos
Main Authors: Busche, Marc N., Stahl, Gregory L.
Formato: Artigo
Idioma:Inglês
Publicado em: German Medical Science GMS Publishing House 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940219/
https://ncbi.nlm.nih.gov/pubmed/20930931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3205/000109
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