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Cellular distribution of insulin-degrading enzyme gene expression. Comparison with insulin and insulin-like growth factor receptors.

Insulin-degrading enzyme (IDE) hydrolyzes both insulin and IGFs and has been proposed to play a role in signal termination after binding of these peptides to their receptors. In situ hybridization was used to investigate the cellular distribution of IDE mRNA and to compare it with insulin receptor (...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bondy, C A, Zhou, J, Chin, E, Reinhardt, R R, Ding, L, Roth, R A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294007/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132782/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117103
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