A pilot trial of high-dose ursodeoxycholic acid in nonalcoholic steatohepatitis

PURPOSE: Standard dose (13–15 mg/kg) ursodeoxycholic acid (UCDA) is ineffective in the treatment of nonalcoholic steatohepatitis (NASH), however, its immunomodulatory and hepatoprotective effects are dose related. Therefore, we examined the impact of high-dose (28–32 mg/kg) UCDA on aminotransaminase...

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Main Authors: Adams, Leon A., Angulo, Paul, Petz, Jan, Keach, Jill, Lindor, Keith D.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2010
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940007/
https://ncbi.nlm.nih.gov/pubmed/21063487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-010-9195-1
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