17 beta-Estradiol inhibits expression of human interleukin-6 promoter-reporter constructs by a receptor-dependent mechanism.

We previously reported that 17 beta-estradiol inhibits cytokine-stimulated bioassayable IL-6 and the steady-state level of IL-6 mRNA. To determine the molecular basis of this effect, the transient expression of chloramphenicol acetyltransferase (CAT) reporter plasmid driven by the human IL-6 promote...

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Dettagli Bibliografici
Autori principali: Pottratz, S T, Bellido, T, Mocharla, H, Crabb, D, Manolagas, S C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC294000/
https://ncbi.nlm.nih.gov/pubmed/8132780
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