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Structural basis for the activation of PPARγ by oxidized fatty acids

The nuclear receptor PPARγ plays important roles in adipogenesis, immune response and in both lipid and carbohydrate metabolism. Although synthetic agonists for PPARγ are widely used as insulin sensitizers, the identity of the natural ligand(s) for PPARγ is still not clear. Suggested natural ligands...

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Detalhes bibliográficos
Main Authors: Itoh, Toshimasa, Fairall, Louise, Amin, Kush, Inaba, Yuka, Szanto, Attila, Balint, Balint L., Nagy, Laszlo, Yamamoto, Keiko, Schwabe, John W.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939985/
https://ncbi.nlm.nih.gov/pubmed/19172745
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