Gene Delivery of Sarcoplasmic Reticulum Calcium ATPase Inhibits Ventricular Remodeling in Ischemic Mitral Regurgitation

BACKGROUND: Mitral regurgitation (MR) doubles mortality following myocardial infarction (MI). We have demonstrated that MR worsens remodeling after MI, and that early correction reverses remodeling. SERCA2a is downregulated in this process. We hypothesized that upregulating SERCA2a may inhibit remod...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Beeri, Ronen, Chaput, Miguel, Guerrero, J. Luis, Kawase, Yoshiaki, Yosefy, Chaim, Abedat, Suzan, Karakikes, Ioannis, Morel, Charlotte, Tisosky, Ashley, Sullivan, Suzanne, Handschumacher, Mark, Gilon, Dan, Vlahakes, Gus J., Hajjar, Roger J., Levine, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939951/
https://ncbi.nlm.nih.gov/pubmed/20634484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.109.891184
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi