Induction of ER Stress in Macrophages of Tuberculosis Granulomas

BACKGROUND: The endoplasmic reticulum (ER) stress pathway known as the Unfolded Protein Response (UPR) is an adaptive survival pathway that protects cells from the buildup of misfolded proteins, but under certain circumstances it can lead to apoptosis. ER stress has been causally associated with mac...

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Библиографические подробности
Главные авторы: Seimon, Tracie A., Kim, Mi-Jeong, Blumenthal, Antje, Koo, Jovanka, Ehrt, Sabine, Wainwright, Helen, Bekker, Linda-Gail, Kaplan, Gilla, Nathan, Carl, Tabas, Ira, Russell, David G.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939897/
https://ncbi.nlm.nih.gov/pubmed/20856677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012772
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